by: Tahara, Tetsuya; Arita, Masafumi;

Indeno(1,2-b)pyrrole derivatives

Indeno[1,2-b]pyrrole derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen, lower alkyl or carbamoylmethyl, R.sup.2 is halogen or trifluoromethyl, R.sup.3 is hydrogen or halogen, and X is oxygen or sulfur. These compounds are useful as medicines such as drugs for treating cerebral dysfunction, anticonvulsants, antiepileptics and antianxiety drugs.






What is claimed is:

1. An indeno[1,2-b]pyrrole compound of the formula: ##STR5## wherein R.sup.1 is hydrogen, lower alkyl or carbamoylmethyl, R.sup.2 is halogen or trifluoromethyl, R.sup.3 is hydrogen or halogen, and X is oxygen or sulfur.

2. The compound as defined in claim 1 which is 5-chloro-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-one.

3. The compound as defined in claim 1 which is 5-chloro-1-methyl-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-one.

4. The compound as defined in claim 1 which is 6-chloro-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-one.

5. The compound as defined in claim 1 which is 7-chloro-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-one.

6. The compound as defined in claim 1 which is 6-fluoro-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-one.

7. The compound as defined in claim 1 which is 6-fluoro-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-thione.

8. The compound as defined in claim 1 which is 7-fluoro-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-one.

9. The compound as defined in claim 1 which is 5-fluoro-1,2,3,3a,4,8b-hexahydro-indeno[1,2-b]pyrrol-2-one.

10. A pharmaceutical composition useful for treatment of convulsion, epilepsy and anxiety comprising a pharmaceutically acceptable carrier and a therapeutically effective amount for said treatment, of a compound as defined in claim 1.


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