Nonlinear optical material

Miyata, Seizo; Hosomi, Takeshi; Suzuki, Toshio; Watanabe, Toshiyuki; Yamamoto, Hironobu; Hayashi, Akio;

A nonlinear optical material comprising a nitroaniline derivative represented by the following chemical formula: A--CX.sub.2 --R wherein A represents ##STR1## (Y represents at least one group selected from the group consisting of hydrogen, alkyl groups, deuterated alkyl groups and electron donor groups and Z represents hydrogen, deuterium, a methyl group or a deuterated methyl group), X represents hydrogen or deuterium, and R represents an alkoxy group, a deuterated alkoxy group or the same group as A.

This invention relates to an organic nonlinear optical material with large molecular hyperpolarizability .beta. and capable of forming noncentrosymmetric crystals.

Nonlinear optical effects refer to the phenomenon in which, when a very intense light passes through a substance, the substance is polarized by the optical field of the light. The induced polarization generates optical harmonics and the light itself undergoes change during the passing.

This phenomenon was already known before the invention of laser but cam to draw increased attention with the advent of laser beam. Clarification of phenomena such as optical harmonic generation, optical parametric oscillation and amplification, optical phase conjugation, optical bistability and the like (the application of these phenomena to optical active devices has drawn attention recently) owes much to the invention of laser. These nonlinear optical effects can find various applications such as conversion of infrared light to visible light or ultraviolet light, light amplification, light switching, optical modulation and undistorted transmission of optical signals. Nonlinear optical devices are crucial functional materials in optical information processing and optical telecommunication fields which will find increased demand in the future.

Substances showing nonlinear optical effects, such as lithium niobate (LiNbO.sub.3), potassium dihydrogen phosphate (KDP), .beta.-barium borate (BBO) and the like have been studied and some of them have been put into practical application as device material. The substances showing nonlinear optical effects, however, are not restricted to these inorganic dielectrics and are found also in organic compounds. The nonlinear optical effects of organic compounds take place owing to the movement of .pi. electrons delocated in the molecules, and the induced polarization in these organic compounds is far faster and larger than that in the inorganic dielectrics in which the o electrons are strongly bound by the atomic nuclei and which are restricted by their lattice vibration. In fact, 2-methyl-4-nitroaniline (hereinafter referred to as "MNA") shows a figure of merit at least 2,000 times that of lithium niobate B. F. LEVINE et al., J. Apply. Phys., Vol. 50, 2523 (1979)].

For the above reason, active researches have been carried out on organic compounds in order to realize the practical use of nonlinear optical effects, particularly optical second-harmonic generation (hereinafter referred to as "SHG") because, among the nonlinear optical effects, the second-order nonlinear optical effects are expected to find the earliest practical application as optical active device. As a result, there were proposed, as nonlinear optical materials, substances such as MNA (Japanese Patent Application Laid-Open No. 500960/1980), nitropyridine-1-oxide derivative (Japanese Patent Application Laid-Open No. 92870/1981, Japanese Patent Application Laid-Open No. 94333/1981) and the like.

In order for an organic compound to show high second-order nonlinear optical effects, the molecules must have a large dipole moment. As well known, a large dipole moment is effectively obtained by introducing an electron donor group and an electron acceptor group into a molecule.

But, even when this last requirement is satisfied, an important problem remains as the organic compound must form noncentrosymmetric crystal to exhibit second order nonlinear optical effects. And it occurs sometimes that a compound, with large molecular dipole moment, crystallizes in such arrangement that the dipole moments are cancelled as a whole. In that case, the compound has large molecular hyperpolarizability (.beta.) but dosen't show second order nonlinear optical effect because of the centrosymmetry of the crystals or molecular aggregates. In fact, there is a lot of such organic compounds. Therefore, to develop organic material showing as essential requirement, large second order nonlinear effects, it is vitally important to synthesize compound with large molecular hyperpolarizability (.beta.) and capable of forming crystals or molecular aggregates without centrosymmetry.

4-Nitroaniline is an aromatic compound having the simplest electron donor group and electron acceptor group and, as an organic compound, has large molecular hyperpolarizability .beta., but does not show second-order nonlinear optical effects. This is because the crystal forms such a molecular arrangment that the dipole moments are cancelled as a whole and therefore the crystal is centrosymmetric.

The present inventors did extensive research to improve the symmetry of 4-nitroaniline and found that some of its derivatives do not show centrosymmetry when formed into crystals or molecular aggregates. This discovery has led to the completion of the present invention.

Therefore, the object of the present invention is to provide a nonlinear optical material derived from nitroaniline, with large molecular hyperpolarizability .beta., capable of forming noncentrosymmetric molecular crystals of easy growth and processability.

The nonlinear optical material of the present invention for achieving the above object consists of a nitroaniline derivative represented by the following chemical formula:

A--CX.sub.2 --R

wherein A represents ##STR2## (Y represents at least one group selected from the group consisting of hydrogen, alkyl groups, deuterated alkyl groups and electron donor groups and Z represents hydrogen, deuterium, a methyl group or a deuterated methyl group), X represents hydrogen or deuterium, and R represents an alkoxy group, a deuterated alkoxy group or the same group as A.

In A, the preferable positions of substituents are such that the nitro group is at the 4-position of the phenyl group and the alkyl, deuterated alkyl or electron donor group constituting Y is at the 2-position of the phenyl group.

Examples of the alkyl group constituting Y include methyl and ethyl. Examples of the electron donor group constituting Y include methoxy and dimethylamino. The component Y is preferably methyl group, methoxy group, deuterated methyl group or deuterated methoxy group.

The nitroaniline derivative represented by the above chemical formula can be obtained, for example, by reacting the corresponding nitroaniline derivative as starting material with formaldehyde in an appropriately selected solvent at an appropriately selected pH.

Examples of the nitroaniline derivative as starting material include 4-nitroaniline, 3-nitroaniline, 2-methyl-4-nitroaniline, 2-methoxy-4-nitroaniline, 5-methyl-3-nitroaniline, N-methyl-4-nitroaniline, N-methyl-3-nitroaniline, 2-chloro-4-nitroaniline, 2-amino-5-nitropyridine, etc. These compounds are reacted with formaldehyde in a solvent of high solvency such as methanol, ethanol, methyl ethyl ketone, methyl isobutyl ketone, tetrahydrofuran, dimethylformaldehyde or the like.

When a compound of the above chemical formula wherein Y, Z and X are independently hydrogen or deuterium and R is methoxy group or deuterated methoxy group, i.e., N-methoxymethyl-4-nitroaniline, is dissolved in a solvent of high solvency such as alcohol (e.g., methanol, ethanol), a ketone (e.g., acetone, methyl ethyl ketone, methyl isobutyl ketone), tetrahydrofuran, chloroform, dichloromethane, dimethyl sulfoxide, dimethylformamide, dimethylacetamide or the like and then is crystallized in one to three days by the solvent evaporation method or the solvent cooling method, the compound can be obtained as good single crystals having sides of some millimeters.

These molecular crystals belong to the orthorhombic space group P2.sub.1 2.sub.1 2.sub.1 and form a hexa- to tetradecahedron constituted by the planes, 101, 101, 101, 101, 110, 110, 110, 11 0, 120, 120, 120, 120, 010 and 010.

The resulting nitroaniline derivative, when irradiated with an Nd:YAG laser beam (.lambda.=1,064 nm) in powdery state, generates second harmonics of very high intensity and green color. The nitroaniline derivative, in single crystal state, allows phase matching over a wide range and generates second harmonics of far higher intensity than that in powdery state. In general, the propagation constant of fundamental wave and that of harmonics in a crystal do not agree and accordingly, harmonics hardly appear in crystal state. The agreement of these propagation constants is called "phase matching". Unless the phase matching is attained, generation of harmonics cannot be observed. Among organic crystals, only few crystals allow phase matching. The molecular crystals according to the present invention generate second harmonics of high intensity, as mentioned above. Moreover, they allow phase matching over a wide range at the crystal growth surfaces and are superior to conventional substances in this respect, too.

When the fundamental wave is an infrared light of 1-1.2 .mu.m, it occurs in some cases that the fundamental wave overlaps with the overtone absorption of the stretching vibration of C--H bond. Thereby the fundamental wave is absorbed and converted to thermal vibration. Therefore, when a fundamental wave of high intensity passes through crystals, the crystals cause a rise in temperature resulting in change in phase matching condition or change in angle of transmitted light. However, in the case of a particular compound of the present invention wherein the hydrogen of an alkyl group with large overtone absorption is substituted by deuterium, the absorption band is shifted to the longer wavelength side and thereby the above phenomenon can be prevented effectively.

According to the present invention, there can be provided a nonlinear optical material which is active to second-order nonlinear optical effects and has novel properties, by introducing a particular substituent at the amino nitrogen of a nitroaniline derivative which has a large dipole moment and accordingly is highly apt to form centrosymmetric crystals, or by bonding two nitroaniline derivatives with a methylene bond to reduce the symmetry of the nitroaniline derivative(s).

The present invention is explained below by means of Examples.

EXAMPLE 1

6.9 g (50 mmol) of 4-nitroaniline was dissolved in 100 ml of methanol. Thereto was added a solution obtained by diluting 10 g of 37% aqueous formaldehyde solution with 20 ml of methanol, and the resulting mixture was reacted for 3 hours at room temperature with stirring. After the completion of the reaction, the reaction mixture was concentrated. The resulting precipitate was collected by filtration, washed with 20-ml portions of methanol three times and then dried at 50.degree. C. under reduced pressure to obtain N,N'-bis-(4-nitrophenyl)-methanediamine.

The physical properties and analytical results of the compound obtained are as follows.

Melting point: 240.degree. C. (measured by DSC)

Molecular weight: 288 (measured by FD-MS)

Analytical results:

.sup.1 H-NMR (solvent: deuterated acetone): .delta.8.05, 4H, doublet, Ar-H, .delta.7.18, 2H, singlet, N-H, .delta.6.90, 4H, doublet, Ar-H, .delta.4.97, 2H, triplet, C-H.sub.2

IR (KBr tablet): 3400 cm.sup.-1, Ar-NH-R, 1260 cm.sup.-1, appearance of Ar-NH-R, etc., 1620 cm.sup.-1, disappearance of NH.sub.2

EXAMPLE 2

320 mg of sodium hydroxide was dissolved in 400 ml of methanol. Thereto was added 20 g of a 37% aqueous formaldehyde solution, and the resulting mixture was reacted for 30 minutes at room temperature with stirring. Thereto was added 13.8 g of 4-nitroaniline and the resulting mixture was reacted for 6 hours at room temperature with stirring. After the completion of the reaction, the reaction mixture was poured into 2,000 ml of water and the resulting precipitate was collected by filtration.

The precipitate (reaction product) was dried under reduced pressure and then recrystallized from tetrahydrofuran to obtain N-methoxymethyl-4-nitroaniline as light yellow, transparent, stick-shaped crystals.

The physical properties and analytical results of the compound obtained are as follows.

Melting point: 115.degree. C. (measured by DSC)

Molecular weight: 182 (measured by FD-MS)

Analytical results:

.sup.1 H-NMR (solvent: deuterated acetone): .delta.8.02, 2H, doublet, Ar-H, .delta.7.22, 1H, singlet, N-H, .delta.6.86, 2H, doublet, Ar-H, .delta.4.67, 2H, doublet, C-H.sub.2, .delta.3.22, 3H, singlet, C-H.sub.3

IR (KBr tablet): 3330 cm.sup.-1, Ar-NH-R, 1150, 1070 cm.sup.-1, C-O-C, 2850 cm.sup.-1, appearance of --OCH.sub.3, etc., 1620 cm.sup.-1, disappearance of NH.sub.2

EXAMPLES 3-12

According to the above procedures, there were synthesized various nitroaniline derivatives wherein X is hydrogen and Y, Z and R each represent various groups as shown in Table 1.

• Belt meandering motion correction device Ball screw tire tread guide
• Anatomical educational amusement ride Welded vehicle wheel
• Optical semiconductor device Coating and bonding composition
• Fast find fundamental method Inhibitors of trypsin-like enzymes
• Tire molding press Removable latch mechanism
• Remedy for respiratory-tract viral disease Flagstaff with hand salute figure
• Combinations of solenoids and motors Humbucking pickup for electric guitar
• Multipurpose exercise machine Metal-free dithiophosphoric acid derivatives
• Semiconductor device High voltage cable splice protector
• Reducible volume containers Countercurrent drum mixer asphalt plant
• Superthermoelastic resonators Artificial bone graft implant
• Projector Epoxy bond diamond saw
• Miticidal (2-alkyl-3,4-dihydro-2H-1-benzopyran-8-yl)-diazenecarboxylic acid esters Class specific classifier
• Automatic sewage valve Press-molded optical element
• Overbased sulfonates Inflatable mattresses
• Multiple part cutting tool Polyimide film-forming polyamide acid solution
• Colonic endoprosthesis Steerable wheeled garment bag
• Absorption refrigeration system Exhaust gas recirculation valve assembly
• Helix-loaded spiral antenna Production of 3,4-dihydroxy phospholane oxides
• Production of laminated materials Cutting insert assembly
• Electronic minnow counter Propulsion device
• Surface active N-Halamine compounds Physiologically active porcine peptide (CNP-53)
• Process for purifying organic solutions Multiprocessor-type fast fourier-analyzer
• Swivel hitch structure Centerless-drive solar collector system
• Use of conjugated linoleic acids Method for crystallizing thermoplastic material
• Helical antenna element Auxiliary wheeled frame for wheelbarrows
• Motorized skateboard Hose swivel
• Transversely engaged centrifugal clutch Breakaway orthodontic face bow appliance
• Styrene-butadiene rubber for truck tires Fuel control apparatus
• Line sawtooth deflection current generator Implement hitch
• 10,11-methylenedioxy-20(RS)-camptothecin and 10,11-methylenedioxy-20(S)-camptothecin analogs Process for single-step coal liquefaction
• Radiation curable coating compositions Coating compositions and processes
• Asbestos free friction materials Lipstick housing having increased strength
• Orthodontic bonding system Guide apparatus for trailer hitch
• Massager unit Wrist mounted map holder apparatus
• Exterior ductwork system Production of radial glial cells
• Low drop out switching regulator X-ray source interlock apparatus

Each of the nitroaniline derivatives obtained in Examples 1-12 was made of particles with diameters of 60-100 .mu.m. These particulate samples were sandwiched between two slide glasses and irradiated with a pulse of 10 nsec using a Q-switched Nd:YAG laser (.lambda.=1064 nm). The intensity of the second harmonics generated from the samples was measured. The intensity of SHG (second-harmonic generation) was expressed as a relative intensity ratio when the intensity of urea was taken as 1. The results are shown in Table 1.

                                      TABLE 1
    __________________________________________________________________________
           Substituents of nitroaniline derivatives
                                 SHG intensity
                           Position of
                                 (ratio to
           X  Y     Z  R   nitro group
                                 urea powders)
    __________________________________________________________________________
    Example 1
           H  H     H  A   4-    120
    Example 2
           H  H     H  OCH.sub.3
                           4-    50
    Example 3
           H  2-CH.sub.3
                    H  OCH.sub.3
                           4-    50
    Example 4
           H  2-CH.sub.3 O
                    H  OCH.sub.3
                           4-    20
    Example 5
           H  H     CH.sub.3
                       OCH.sub.3
                           4-    35
    Example 6
           H  2-CH.sub.3
                    H  A   4-    35
    Example 7
           H  2-CH.sub.3 O
                    H  A   4-    10
    Example 8
           H  2-(CH.sub.3).sub.2 N
                    H  A   4-    32
    Example 9
           H  H     CH.sub.3
                       A   4-    10
    Example 10
           H  2-CH.sub.3
                    CH.sub.3
                       A   4-     9
    Example 11
           H  2-CH.sub.3 O
                    CH.sub.3
                       A   4-     5
    Example 12
           H  2-CH.sub.3
                    H  A   5-    26
    Comparative
           MNA                   22
    Example
    __________________________________________________________________________

                                      TABLE 2
    __________________________________________________________________________
           Substituents of deutreated
           nitroaniline derivatives
                                 SHG intensity
                           Position of
                                 (ratio to
           X  Y     Z  R   nitro group
                                 urea powders)
    __________________________________________________________________________
    Example 13
           D  H     D  A   4-    116
    Example 14
           D  2-CH.sub.3
                    D  A   4-    39
    Example 15
           D  2-CD.sub.3
                    D  A   4-    36
    Example 16
           D  2-CD.sub.3 O
                    CD.sub.3
                       A   4-    10
    Example 17
           D  H     H  OCD.sub.3
                           4-    50
    Example 18
           D  2-CH.sub.3
                    H  OCD.sub.3
                           4-    50
    Example 19
           D  2-CD.sub.3
                    H  OCD.sub.3
                           4-    50
    __________________________________________________________________________

                  TABLE 3
    ______________________________________
    Lattice constants
    a     b         c       .alpha. .beta.
                                          .gamma.
    (.ANG.)
          (.ANG.)   (.ANG.) (.degree.)
                                    (.degree.)
                                          (.degree.)
    ______________________________________
    11.2347
          17.5519   4.5708  90.013  89.977
                                          89.941
    ______________________________________